Isoendoxan en es it fr

Isoendoxan Brand names, Isoendoxan Analogs

Isoendoxan Brand Names Mixture

  • No information avaliable

Isoendoxan Chemical_Formula


Isoendoxan RX_link

Isoendoxan fda sheet

Isoendoxan msds (material safety sheet)

Isoendoxan MSDS

Isoendoxan Synthesis Reference

No information avaliable

Isoendoxan Molecular Weight

261.085 g/mol

Isoendoxan Melting Point

39-41 oC

Isoendoxan H2O Solubility

3780 mg/L

Isoendoxan State


Isoendoxan LogP


Isoendoxan Dosage Forms

Powder for constitution and administration by intravenous infusion

Isoendoxan Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Isoendoxan Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Isoendoxan Absorption

No information avaliable

Isoendoxan side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Isoendoxan Patient Information

No information avaliable

Isoendoxan Organisms Affected

Humans and other mammals