Holoxan 1000 en es it fr

Holoxan 1000 Brand names, Holoxan 1000 Analogs

Holoxan 1000 Brand Names Mixture

  • No information avaliable

Holoxan 1000 Chemical_Formula


Holoxan 1000 RX_link


Holoxan 1000 fda sheet


Holoxan 1000 msds (material safety sheet)

Holoxan_1000 MSDS

Holoxan 1000 Synthesis Reference

No information avaliable

Holoxan 1000 Molecular Weight

261.085 g/mol

Holoxan 1000 Melting Point

39-41 oC

Holoxan 1000 H2O Solubility

3780 mg/L

Holoxan 1000 State


Holoxan 1000 LogP


Holoxan 1000 Dosage Forms

Powder for constitution and administration by intravenous infusion

Holoxan 1000 Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Holoxan 1000 Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Holoxan 1000 Absorption

No information avaliable

Holoxan 1000 side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Holoxan 1000 Patient Information

No information avaliable

Holoxan 1000 Organisms Affected

Humans and other mammals