Iphosphamid en es it fr

Iphosphamid Brand names, Iphosphamid Analogs

Iphosphamid Brand Names Mixture

  • No information avaliable

Iphosphamid Chemical_Formula


Iphosphamid RX_link


Iphosphamid fda sheet


Iphosphamid msds (material safety sheet)

Iphosphamid MSDS

Iphosphamid Synthesis Reference

No information avaliable

Iphosphamid Molecular Weight

261.085 g/mol

Iphosphamid Melting Point

39-41 oC

Iphosphamid H2O Solubility

3780 mg/L

Iphosphamid State


Iphosphamid LogP


Iphosphamid Dosage Forms

Powder for constitution and administration by intravenous infusion

Iphosphamid Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Iphosphamid Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Iphosphamid Absorption

No information avaliable

Iphosphamid side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Iphosphamid Patient Information

No information avaliable

Iphosphamid Organisms Affected

Humans and other mammals