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Iphosphamide Brand names, Iphosphamide Analogs

Iphosphamide Brand Names Mixture

  • No information avaliable

Iphosphamide Chemical_Formula


Iphosphamide RX_link


Iphosphamide fda sheet


Iphosphamide msds (material safety sheet)

Iphosphamide MSDS

Iphosphamide Synthesis Reference

No information avaliable

Iphosphamide Molecular Weight

261.085 g/mol

Iphosphamide Melting Point

39-41 oC

Iphosphamide H2O Solubility

3780 mg/L

Iphosphamide State


Iphosphamide LogP


Iphosphamide Dosage Forms

Powder for constitution and administration by intravenous infusion

Iphosphamide Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Iphosphamide Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Iphosphamide Absorption

No information avaliable

Iphosphamide side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Iphosphamide Patient Information

No information avaliable

Iphosphamide Organisms Affected

Humans and other mammals