Guaiphenesin carbamate en es it fr

Guaiphenesin carbamate Brand names, Guaiphenesin carbamate Analogs

Guaiphenesin carbamate Brand Names Mixture

  • No information avaliable

Guaiphenesin carbamate Chemical_Formula

C14H14N2O

Guaiphenesin carbamate RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

Guaiphenesin carbamate fda sheet

Guaiphenesin carbamate msds (material safety sheet)

Guaiphenesin carbamate Synthesis Reference

No information avaliable

Guaiphenesin carbamate Molecular Weight

226.274 g/mol

Guaiphenesin carbamate Melting Point

50.5 oC

Guaiphenesin carbamate H2O Solubility

Sparingly soluble

Guaiphenesin carbamate State

Solid

Guaiphenesin carbamate LogP

2.303

Guaiphenesin carbamate Dosage Forms

Capsules for oral administration (250 mg)

Guaiphenesin carbamate Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Guaiphenesin carbamate Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Guaiphenesin carbamate Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Guaiphenesin carbamate side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Guaiphenesin carbamate Patient Information

Guaiphenesin carbamate Organisms Affected

Humans and other mammals