Guaiacol glyceryl ether carbamate en es it fr

Guaiacol glyceryl ether carbamate Brand names, Guaiacol glyceryl ether carbamate Analogs

Guaiacol glyceryl ether carbamate Brand Names Mixture

  • No information avaliable

Guaiacol glyceryl ether carbamate Chemical_Formula

C14H14N2O

Guaiacol glyceryl ether carbamate RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

Guaiacol glyceryl ether carbamate fda sheet

Guaiacol glyceryl ether carbamate msds (material safety sheet)

Guaiacol glyceryl ether carbamate Synthesis Reference

No information avaliable

Guaiacol glyceryl ether carbamate Molecular Weight

226.274 g/mol

Guaiacol glyceryl ether carbamate Melting Point

50.5 oC

Guaiacol glyceryl ether carbamate H2O Solubility

Sparingly soluble

Guaiacol glyceryl ether carbamate State

Solid

Guaiacol glyceryl ether carbamate LogP

2.303

Guaiacol glyceryl ether carbamate Dosage Forms

Capsules for oral administration (250 mg)

Guaiacol glyceryl ether carbamate Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Guaiacol glyceryl ether carbamate Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Guaiacol glyceryl ether carbamate Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Guaiacol glyceryl ether carbamate side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Guaiacol glyceryl ether carbamate Patient Information

Guaiacol glyceryl ether carbamate Organisms Affected

Humans and other mammals