Avetil en es it fr

Avetil Brand names, Avetil Analogs

Avetil Brand Names Mixture

  • No information avaliable

Avetil Chemical_Formula

C14H14N2O

Avetil RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

Avetil fda sheet

Avetil msds (material safety sheet)

Avetil Synthesis Reference

No information avaliable

Avetil Molecular Weight

226.274 g/mol

Avetil Melting Point

50.5 oC

Avetil H2O Solubility

Sparingly soluble

Avetil State

Solid

Avetil LogP

2.303

Avetil Dosage Forms

Capsules for oral administration (250 mg)

Avetil Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Avetil Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Avetil Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Avetil side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Avetil Patient Information

Avetil Organisms Affected

Humans and other mammals