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Robaxan Brand names, Robaxan Analogs

Robaxan Brand Names Mixture

  • No information avaliable

Robaxan Chemical_Formula

C14H14N2O

Robaxan RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

Robaxan fda sheet

Robaxan msds (material safety sheet)

Robaxan Synthesis Reference

No information avaliable

Robaxan Molecular Weight

226.274 g/mol

Robaxan Melting Point

50.5 oC

Robaxan H2O Solubility

Sparingly soluble

Robaxan State

Solid

Robaxan LogP

2.303

Robaxan Dosage Forms

Capsules for oral administration (250 mg)

Robaxan Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Robaxan Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Robaxan Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Robaxan side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Robaxan Patient Information

Robaxan Organisms Affected

Humans and other mammals