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Romethocarb Brand names, Romethocarb Analogs

Romethocarb Brand Names Mixture

  • No information avaliable

Romethocarb Chemical_Formula


Romethocarb RX_link

Romethocarb fda sheet

Romethocarb msds (material safety sheet)

Romethocarb Synthesis Reference

No information avaliable

Romethocarb Molecular Weight

226.274 g/mol

Romethocarb Melting Point

50.5 oC

Romethocarb H2O Solubility

Sparingly soluble

Romethocarb State


Romethocarb LogP


Romethocarb Dosage Forms

Capsules for oral administration (250 mg)

Romethocarb Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Romethocarb Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Romethocarb Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Romethocarb side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Romethocarb Patient Information

Romethocarb Organisms Affected

Humans and other mammals