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AHR 85 Brand names, AHR 85 Analogs

AHR 85 Brand Names Mixture

  • No information avaliable

AHR 85 Chemical_Formula

C14H14N2O

AHR 85 RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

AHR 85 fda sheet

AHR 85 msds (material safety sheet)

AHR 85 Synthesis Reference

No information avaliable

AHR 85 Molecular Weight

226.274 g/mol

AHR 85 Melting Point

50.5 oC

AHR 85 H2O Solubility

Sparingly soluble

AHR 85 State

Solid

AHR 85 LogP

2.303

AHR 85 Dosage Forms

Capsules for oral administration (250 mg)

AHR 85 Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

AHR 85 Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

AHR 85 Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

AHR 85 side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

AHR 85 Patient Information

AHR 85 Organisms Affected

Humans and other mammals