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Miolaxene Brand names, Miolaxene Analogs

Miolaxene Brand Names Mixture

  • No information avaliable

Miolaxene Chemical_Formula

C14H14N2O

Miolaxene RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

Miolaxene fda sheet

Miolaxene msds (material safety sheet)

Miolaxene Synthesis Reference

No information avaliable

Miolaxene Molecular Weight

226.274 g/mol

Miolaxene Melting Point

50.5 oC

Miolaxene H2O Solubility

Sparingly soluble

Miolaxene State

Solid

Miolaxene LogP

2.303

Miolaxene Dosage Forms

Capsules for oral administration (250 mg)

Miolaxene Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Miolaxene Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Miolaxene Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Miolaxene side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Miolaxene Patient Information

Miolaxene Organisms Affected

Humans and other mammals