Glycerylguajacol-Carbamat en es it fr

Glycerylguajacol-Carbamat Brand names, Glycerylguajacol-Carbamat Analogs

Glycerylguajacol-Carbamat Brand Names Mixture

  • No information avaliable

Glycerylguajacol-Carbamat Chemical_Formula

C14H14N2O

Glycerylguajacol-Carbamat RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

Glycerylguajacol-Carbamat fda sheet

Glycerylguajacol-Carbamat msds (material safety sheet)

Glycerylguajacol-Carbamat Synthesis Reference

No information avaliable

Glycerylguajacol-Carbamat Molecular Weight

226.274 g/mol

Glycerylguajacol-Carbamat Melting Point

50.5 oC

Glycerylguajacol-Carbamat H2O Solubility

Sparingly soluble

Glycerylguajacol-Carbamat State

Solid

Glycerylguajacol-Carbamat LogP

2.303

Glycerylguajacol-Carbamat Dosage Forms

Capsules for oral administration (250 mg)

Glycerylguajacol-Carbamat Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Glycerylguajacol-Carbamat Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Glycerylguajacol-Carbamat Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Glycerylguajacol-Carbamat side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Glycerylguajacol-Carbamat Patient Information

Glycerylguajacol-Carbamat Organisms Affected

Humans and other mammals