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Miorilas Brand names, Miorilas Analogs

Miorilas Brand Names Mixture

  • No information avaliable

Miorilas Chemical_Formula

C14H14N2O

Miorilas RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

Miorilas fda sheet

Miorilas msds (material safety sheet)

Miorilas Synthesis Reference

No information avaliable

Miorilas Molecular Weight

226.274 g/mol

Miorilas Melting Point

50.5 oC

Miorilas H2O Solubility

Sparingly soluble

Miorilas State

Solid

Miorilas LogP

2.303

Miorilas Dosage Forms

Capsules for oral administration (250 mg)

Miorilas Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Miorilas Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Miorilas Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Miorilas side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Miorilas Patient Information

Miorilas Organisms Affected

Humans and other mammals