Metofenia en es it fr

Metofenia Brand names, Metofenia Analogs

Metofenia Brand Names Mixture

  • No information avaliable

Metofenia Chemical_Formula

C14H14N2O

Metofenia RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

Metofenia fda sheet

Metofenia msds (material safety sheet)

Metofenia Synthesis Reference

No information avaliable

Metofenia Molecular Weight

226.274 g/mol

Metofenia Melting Point

50.5 oC

Metofenia H2O Solubility

Sparingly soluble

Metofenia State

Solid

Metofenia LogP

2.303

Metofenia Dosage Forms

Capsules for oral administration (250 mg)

Metofenia Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Metofenia Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Metofenia Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Metofenia side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Metofenia Patient Information

Metofenia Organisms Affected

Humans and other mammals