Guaiphenesine carbamate en es it fr

Guaiphenesine carbamate Brand names, Guaiphenesine carbamate Analogs

Guaiphenesine carbamate Brand Names Mixture

  • No information avaliable

Guaiphenesine carbamate Chemical_Formula

C14H14N2O

Guaiphenesine carbamate RX_link

http://www.rxlist.com/cgi/generic3/metopirone.htm

Guaiphenesine carbamate fda sheet

Guaiphenesine carbamate msds (material safety sheet)

Guaiphenesine carbamate Synthesis Reference

No information avaliable

Guaiphenesine carbamate Molecular Weight

226.274 g/mol

Guaiphenesine carbamate Melting Point

50.5 oC

Guaiphenesine carbamate H2O Solubility

Sparingly soluble

Guaiphenesine carbamate State

Solid

Guaiphenesine carbamate LogP

2.303

Guaiphenesine carbamate Dosage Forms

Capsules for oral administration (250 mg)

Guaiphenesine carbamate Indication

Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.

Guaiphenesine carbamate Pharmacology

Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.

Guaiphenesine carbamate Absorption

Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.

Guaiphenesine carbamate side effects and Toxicity

Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.

Guaiphenesine carbamate Patient Information

Guaiphenesine carbamate Organisms Affected

Humans and other mammals