Delaxin
Brand names,
Delaxin
Analogs
Delaxin
Brand Names Mixture
Delaxin
Chemical_Formula
C14H14N2O
Delaxin
RX_link
http://www.rxlist.com/cgi/generic3/metopirone.htm
Delaxin
fda sheet
Delaxin
msds (material safety sheet)
Delaxin
Synthesis Reference
No information avaliable
Delaxin
Molecular Weight
226.274 g/mol
Delaxin
Melting Point
50.5 oC
Delaxin
H2O Solubility
Sparingly soluble
Delaxin
State
Solid
Delaxin
LogP
2.303
Delaxin
Dosage Forms
Capsules for oral administration (250 mg)
Delaxin
Indication
Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.
Delaxin
Pharmacology
Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.
Delaxin
Absorption
Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.
Delaxin
side effects and Toxicity
Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.
Delaxin
Patient Information
Delaxin
Organisms Affected
Humans and other mammals