Lumirelax
Brand names,
Lumirelax
Analogs
Lumirelax
Brand Names Mixture
Lumirelax
Chemical_Formula
C14H14N2O
Lumirelax
RX_link
http://www.rxlist.com/cgi/generic3/metopirone.htm
Lumirelax
fda sheet
Lumirelax
msds (material safety sheet)
Lumirelax
Synthesis Reference
No information avaliable
Lumirelax
Molecular Weight
226.274 g/mol
Lumirelax
Melting Point
50.5 oC
Lumirelax
H2O Solubility
Sparingly soluble
Lumirelax
State
Solid
Lumirelax
LogP
2.303
Lumirelax
Dosage Forms
Capsules for oral administration (250 mg)
Lumirelax
Indication
Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function.
Lumirelax
Pharmacology
Metopirone is an inhibitor of endogenous adrenal corticosteroid synthesis.
Lumirelax
Absorption
Absorbed rapidly and well when administered orally. Peak plasma concentrations are usually reached 1 hour after administration.
Lumirelax
side effects and Toxicity
Oral LD50 in rats is 521 mg/kg. One case has been recorded in which a 6-year-old girl died after two doses of Metopirone, 2 g. Symptoms of overdose include cardiac arrhythmias, hypotension, dehydration, anxiety, confusion, weakness, impairment of consciousness, nausea, vomiting, epigastric pain, and diarrhea.
Lumirelax
Patient Information
Lumirelax
Organisms Affected
Humans and other mammals