Fludrocortisone

• Anti-inflammatory Agents
• Adrenergic Agents
• ATC:H02AA02

• 9 .Alpha. Ff
• 9 Alpha Ff
• 9 alpha-Fludrocortisone
• 9 alpha-Fluorocortisol
• 9.Alpha.-Fluorocortisol
• 9.Alpha.-Fluorohydrocortisone
• Alflorone
• Astonin-H
• F-COL
• F-Cortef
• Florinef
• Fludrocortisona [Inn-Spanish]
• Fludrocortisone Acetate
• Fludrocortisonum [Inn-Latin]
• Fludrocortone
• Fludrone
• Fludronef
• Fluodrocortisone
• Fluohydrisone
• Fluohydrocortisone
• Fluorocortisol
• Fluorocortisone
• ZK5

• No information avaliable

C₂₁H₂₉FO₅

http://www.rxlist.com/cgi/generic/fludro.htm

Fludrocortisone MSDS

No information avaliable

380.45 g/mol

No information avaliable

140 mg/L

Solid

1.49

Tablet

For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.

Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.

No information avaliable

Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.

Humans and other mammals