Fludrocortisone
Fludrocortisone Brand names, Fludrocortisone Analogs
- 9 .Alpha. Ff
- 9 Alpha Ff
- 9 alpha-Fludrocortisone
- 9 alpha-Fluorocortisol
- 9.Alpha.-Fluorocortisol
- 9.Alpha.-Fluorohydrocortisone
- Alflorone
- Astonin-H
- F-COL
- F-Cortef
- Florinef
- Fludrocortisona [Inn-Spanish]
- Fludrocortisone Acetate
- Fludrocortisonum [Inn-Latin]
- Fludrocortone
- Fludrone
- Fludronef
- Fluodrocortisone
- Fluohydrisone
- Fluohydrocortisone
- Fluorocortisol
- Fluorocortisone
- ZK5
Fludrocortisone Brand Names Mixture
- No information avaliable
Fludrocortisone Chemical_Formula
C21H29FO5
Fludrocortisone RX_link
http://www.rxlist.com/cgi/generic/fludro.htm
Fludrocortisone fda sheet
Fludrocortisone msds (material safety sheet)
Fludrocortisone Synthesis Reference
No information avaliable
Fludrocortisone Molecular Weight
380.45 g/mol
Fludrocortisone Melting Point
No information avaliable
Fludrocortisone H2O Solubility
140 mg/L
Fludrocortisone State
Solid
Fludrocortisone LogP
1.49
Fludrocortisone Dosage Forms
Tablet
Fludrocortisone Indication
For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.
Fludrocortisone Pharmacology
Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.
Fludrocortisone Absorption
No information avaliable
Fludrocortisone side effects and Toxicity
Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.
Fludrocortisone Patient Information
Fludrocortisone Organisms Affected
Humans and other mammals
