PharmacyCodes



Florinef en es it fr

Florinef Brand names, Florinef Analogs

Florinef Brand Names Mixture

  • No information avaliable

Florinef Chemical_Formula

C21H29FO5

Florinef RX_link

http://www.rxlist.com/cgi/generic/fludro.htm

Florinef fda sheet

Florinef msds (material safety sheet)

Florinef MSDS

Florinef Synthesis Reference

No information avaliable

Florinef Molecular Weight

380.45 g/mol

Florinef Melting Point

No information avaliable

Florinef H2O Solubility

140 mg/L

Florinef State

Solid

Florinef LogP

1.49

Florinef Dosage Forms

Tablet

Florinef Indication

For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.

Florinef Pharmacology

Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.

Florinef Absorption

No information avaliable

Florinef side effects and Toxicity

Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.

Florinef Patient Information

Florinef Organisms Affected

Humans and other mammals