Alflorone
Alflorone Brand names, Alflorone Analogs
- 9 .Alpha. Ff
- 9 Alpha Ff
- 9 alpha-Fludrocortisone
- 9 alpha-Fluorocortisol
- 9.Alpha.-Fluorocortisol
- 9.Alpha.-Fluorohydrocortisone
- Alflorone
- Astonin-H
- F-COL
- F-Cortef
- Florinef
- Fludrocortisona [Inn-Spanish]
- Fludrocortisone Acetate
- Fludrocortisonum [Inn-Latin]
- Fludrocortone
- Fludrone
- Fludronef
- Fluodrocortisone
- Fluohydrisone
- Fluohydrocortisone
- Fluorocortisol
- Fluorocortisone
- ZK5
Alflorone Brand Names Mixture
- No information avaliable
Alflorone Chemical_Formula
C21H29FO5
Alflorone RX_link
http://www.rxlist.com/cgi/generic/fludro.htm
Alflorone fda sheet
Alflorone msds (material safety sheet)
Alflorone Synthesis Reference
No information avaliable
Alflorone Molecular Weight
380.45 g/mol
Alflorone Melting Point
No information avaliable
Alflorone H2O Solubility
140 mg/L
Alflorone State
Solid
Alflorone LogP
1.49
Alflorone Dosage Forms
Tablet
Alflorone Indication
For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.
Alflorone Pharmacology
Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.
Alflorone Absorption
No information avaliable
Alflorone side effects and Toxicity
Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.
Alflorone Patient Information
Alflorone Organisms Affected
Humans and other mammals
