Fludrocortone
Fludrocortone Brand names, Fludrocortone Analogs
- 9 .Alpha. Ff
- 9 Alpha Ff
- 9 alpha-Fludrocortisone
- 9 alpha-Fluorocortisol
- 9.Alpha.-Fluorocortisol
- 9.Alpha.-Fluorohydrocortisone
- Alflorone
- Astonin-H
- F-COL
- F-Cortef
- Florinef
- Fludrocortisona [Inn-Spanish]
- Fludrocortisone Acetate
- Fludrocortisonum [Inn-Latin]
- Fludrocortone
- Fludrone
- Fludronef
- Fluodrocortisone
- Fluohydrisone
- Fluohydrocortisone
- Fluorocortisol
- Fluorocortisone
- ZK5
Fludrocortone Brand Names Mixture
- No information avaliable
Fludrocortone Chemical_Formula
C21H29FO5
Fludrocortone RX_link
http://www.rxlist.com/cgi/generic/fludro.htm
Fludrocortone fda sheet
Fludrocortone msds (material safety sheet)
Fludrocortone Synthesis Reference
No information avaliable
Fludrocortone Molecular Weight
380.45 g/mol
Fludrocortone Melting Point
No information avaliable
Fludrocortone H2O Solubility
140 mg/L
Fludrocortone State
Solid
Fludrocortone LogP
1.49
Fludrocortone Dosage Forms
Tablet
Fludrocortone Indication
For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.
Fludrocortone Pharmacology
Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.
Fludrocortone Absorption
No information avaliable
Fludrocortone side effects and Toxicity
Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.
Fludrocortone Patient Information
Fludrocortone Organisms Affected
Humans and other mammals
