Fluodrocortisone
Fluodrocortisone Brand names, Fluodrocortisone Analogs
- 9 .Alpha. Ff
- 9 Alpha Ff
- 9 alpha-Fludrocortisone
- 9 alpha-Fluorocortisol
- 9.Alpha.-Fluorocortisol
- 9.Alpha.-Fluorohydrocortisone
- Alflorone
- Astonin-H
- F-COL
- F-Cortef
- Florinef
- Fludrocortisona [Inn-Spanish]
- Fludrocortisone Acetate
- Fludrocortisonum [Inn-Latin]
- Fludrocortone
- Fludrone
- Fludronef
- Fluodrocortisone
- Fluohydrisone
- Fluohydrocortisone
- Fluorocortisol
- Fluorocortisone
- ZK5
Fluodrocortisone Brand Names Mixture
- No information avaliable
Fluodrocortisone Chemical_Formula
C21H29FO5
Fluodrocortisone RX_link
http://www.rxlist.com/cgi/generic/fludro.htm
Fluodrocortisone fda sheet
Fluodrocortisone msds (material safety sheet)
Fluodrocortisone Synthesis Reference
No information avaliable
Fluodrocortisone Molecular Weight
380.45 g/mol
Fluodrocortisone Melting Point
No information avaliable
Fluodrocortisone H2O Solubility
140 mg/L
Fluodrocortisone State
Solid
Fluodrocortisone LogP
1.49
Fluodrocortisone Dosage Forms
Tablet
Fluodrocortisone Indication
For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.
Fluodrocortisone Pharmacology
Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.
Fluodrocortisone Absorption
No information avaliable
Fluodrocortisone side effects and Toxicity
Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.
Fluodrocortisone Patient Information
Fluodrocortisone Organisms Affected
Humans and other mammals
