Fludronef
Fludronef Brand names, Fludronef Analogs
- 9 .Alpha. Ff
- 9 Alpha Ff
- 9 alpha-Fludrocortisone
- 9 alpha-Fluorocortisol
- 9.Alpha.-Fluorocortisol
- 9.Alpha.-Fluorohydrocortisone
- Alflorone
- Astonin-H
- F-COL
- F-Cortef
- Florinef
- Fludrocortisona [Inn-Spanish]
- Fludrocortisone Acetate
- Fludrocortisonum [Inn-Latin]
- Fludrocortone
- Fludrone
- Fludronef
- Fluodrocortisone
- Fluohydrisone
- Fluohydrocortisone
- Fluorocortisol
- Fluorocortisone
- ZK5
Fludronef Brand Names Mixture
- No information avaliable
Fludronef Chemical_Formula
C21H29FO5
Fludronef RX_link
http://www.rxlist.com/cgi/generic/fludro.htm
Fludronef fda sheet
Fludronef msds (material safety sheet)
Fludronef Synthesis Reference
No information avaliable
Fludronef Molecular Weight
380.45 g/mol
Fludronef Melting Point
No information avaliable
Fludronef H2O Solubility
140 mg/L
Fludronef State
Solid
Fludronef LogP
1.49
Fludronef Dosage Forms
Tablet
Fludronef Indication
For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.
Fludronef Pharmacology
Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.
Fludronef Absorption
No information avaliable
Fludronef side effects and Toxicity
Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.
Fludronef Patient Information
Fludronef Organisms Affected
Humans and other mammals
