ZK5
ZK5 Brand names, ZK5 Analogs
- 9 .Alpha. Ff
- 9 Alpha Ff
- 9 alpha-Fludrocortisone
- 9 alpha-Fluorocortisol
- 9.Alpha.-Fluorocortisol
- 9.Alpha.-Fluorohydrocortisone
- Alflorone
- Astonin-H
- F-COL
- F-Cortef
- Florinef
- Fludrocortisona [Inn-Spanish]
- Fludrocortisone Acetate
- Fludrocortisonum [Inn-Latin]
- Fludrocortone
- Fludrone
- Fludronef
- Fluodrocortisone
- Fluohydrisone
- Fluohydrocortisone
- Fluorocortisol
- Fluorocortisone
- ZK5
ZK5 Brand Names Mixture
- No information avaliable
ZK5 Chemical_Formula
C21H29FO5
ZK5 RX_link
http://www.rxlist.com/cgi/generic/fludro.htm
ZK5 fda sheet
ZK5 msds (material safety sheet)
ZK5 Synthesis Reference
No information avaliable
ZK5 Molecular Weight
380.45 g/mol
ZK5 Melting Point
No information avaliable
ZK5 H2O Solubility
140 mg/L
ZK5 State
Solid
ZK5 LogP
1.49
ZK5 Dosage Forms
Tablet
ZK5 Indication
For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.
ZK5 Pharmacology
Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.
ZK5 Absorption
No information avaliable
ZK5 side effects and Toxicity
Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.
ZK5 Patient Information
ZK5 Organisms Affected
Humans and other mammals
