Fluorocortisone
Fluorocortisone Brand names, Fluorocortisone Analogs
- 9 .Alpha. Ff
- 9 Alpha Ff
- 9 alpha-Fludrocortisone
- 9 alpha-Fluorocortisol
- 9.Alpha.-Fluorocortisol
- 9.Alpha.-Fluorohydrocortisone
- Alflorone
- Astonin-H
- F-COL
- F-Cortef
- Florinef
- Fludrocortisona [Inn-Spanish]
- Fludrocortisone Acetate
- Fludrocortisonum [Inn-Latin]
- Fludrocortone
- Fludrone
- Fludronef
- Fluodrocortisone
- Fluohydrisone
- Fluohydrocortisone
- Fluorocortisol
- Fluorocortisone
- ZK5
Fluorocortisone Brand Names Mixture
- No information avaliable
Fluorocortisone Chemical_Formula
C21H29FO5
Fluorocortisone RX_link
http://www.rxlist.com/cgi/generic/fludro.htm
Fluorocortisone fda sheet
Fluorocortisone msds (material safety sheet)
Fluorocortisone Synthesis Reference
No information avaliable
Fluorocortisone Molecular Weight
380.45 g/mol
Fluorocortisone Melting Point
No information avaliable
Fluorocortisone H2O Solubility
140 mg/L
Fluorocortisone State
Solid
Fluorocortisone LogP
1.49
Fluorocortisone Dosage Forms
Tablet
Fluorocortisone Indication
For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.
Fluorocortisone Pharmacology
Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.
Fluorocortisone Absorption
No information avaliable
Fluorocortisone side effects and Toxicity
Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.
Fluorocortisone Patient Information
Fluorocortisone Organisms Affected
Humans and other mammals
