Fludrocortisone Acetate
Fludrocortisone Acetate Brand names, Fludrocortisone Acetate Analogs
- 9 .Alpha. Ff
- 9 Alpha Ff
- 9 alpha-Fludrocortisone
- 9 alpha-Fluorocortisol
- 9.Alpha.-Fluorocortisol
- 9.Alpha.-Fluorohydrocortisone
- Alflorone
- Astonin-H
- F-COL
- F-Cortef
- Florinef
- Fludrocortisona [Inn-Spanish]
- Fludrocortisone Acetate
- Fludrocortisonum [Inn-Latin]
- Fludrocortone
- Fludrone
- Fludronef
- Fluodrocortisone
- Fluohydrisone
- Fluohydrocortisone
- Fluorocortisol
- Fluorocortisone
- ZK5
Fludrocortisone Acetate Brand Names Mixture
- No information avaliable
Fludrocortisone Acetate Chemical_Formula
C21H29FO5
Fludrocortisone Acetate RX_link
http://www.rxlist.com/cgi/generic/fludro.htm
Fludrocortisone Acetate fda sheet
Fludrocortisone Acetate msds (material safety sheet)
Fludrocortisone Acetate Synthesis Reference
No information avaliable
Fludrocortisone Acetate Molecular Weight
380.45 g/mol
Fludrocortisone Acetate Melting Point
No information avaliable
Fludrocortisone Acetate H2O Solubility
140 mg/L
Fludrocortisone Acetate State
Solid
Fludrocortisone Acetate LogP
1.49
Fludrocortisone Acetate Dosage Forms
Tablet
Fludrocortisone Acetate Indication
For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.
Fludrocortisone Acetate Pharmacology
Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.
Fludrocortisone Acetate Absorption
No information avaliable
Fludrocortisone Acetate side effects and Toxicity
Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.
Fludrocortisone Acetate Patient Information
Fludrocortisone Acetate Organisms Affected
Humans and other mammals
