Dilacor
Brand names,
Dilacor
Analogs
Dilacor
Brand Names Mixture
- Tarka (trandolapril + verapamil hydrochloride)
Dilacor
Chemical_Formula
C27H38N2O4
Dilacor
RX_link
http://www.rxlist.com/cgi/generic/verapsr.htm
Dilacor
fda sheet
Dilacor
msds (material safety sheet)
Dilacor
Synthesis Reference
Dengel, U.S. Pat. 3,261,859 (1966)
Dilacor
Molecular Weight
454.602 g/mol
Dilacor
Melting Point
< 25 oC
Dilacor
H2O Solubility
4.47 mg/L
Dilacor
State
Liquid
Dilacor
LogP
5.931
Dilacor
Dosage Forms
Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)
Dilacor
Indication
For the treatment of hypertension and angina.
Dilacor
Pharmacology
Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.
Dilacor
Absorption
90%
Dilacor
side effects and Toxicity
LD50=8 mg/kg (i.v. in mice)
Dilacor
Patient Information
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Dilacor
Organisms Affected
Humans and other mammals