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ASTA Brand names, ASTA Analogs

ASTA Brand Names Mixture

  • No information avaliable

ASTA Chemical_Formula


ASTA RX_link

ASTA fda sheet

ASTA msds (material safety sheet)


ASTA Synthesis Reference

No information avaliable

ASTA Molecular Weight

261.085 g/mol

ASTA Melting Point

39-41 oC

ASTA H2O Solubility

3780 mg/L

ASTA State




ASTA Dosage Forms

Powder for constitution and administration by intravenous infusion

ASTA Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

ASTA Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

ASTA Absorption

No information avaliable

ASTA side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

ASTA Patient Information

No information avaliable

ASTA Organisms Affected

Humans and other mammals