Ingastri

Category

Ingastri




Useful info

Ingastri Brand names, Ingastri Analogs

Ingastri Brand Names Mixture

  • No information avaliable

    • Ingastri Chemical_Formula

    C8H15N7O2S3

    Ingastri RX_link

    http://www.rxlist.com/cgi/generic/famot.htm

    Ingastri fda sheet

    Ingastri FDA

    Ingastri msds (material safety sheet)

    Ingastri MSDS

    Ingastri Synthesis Reference

    H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

    Ingastri Molecular Weight

    337.449 g/mol

    Ingastri Melting Point

    163-164 oC

    Ingastri H2O Solubility

    1.1 mg/mL

    Ingastri State

    Solid

    Ingastri LogP

    -0.726

    Ingastri Dosage Forms

    Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

    Ingastri Indication

    For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

    Ingastri Pharmacology

    Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

    Ingastri Absorption

    The bioavailability of oral doses is 40-45%.

    Ingastri Toxicity

    Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

    Ingastri Patient Information

    Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
    hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
    reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
    physician if you are pregnant or nursing. Famotidine may be taken with or without food.
    Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
    suspension should be discarded after 30 days. Notify your physician if you develop black,
    tarry stools or coffee-ground vomit.

    Ingastri Organisms Affected

    Humans and other mammals