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Dispronil Brand names, Dispronil Analogs

Dispronil Brand Names Mixture

  • No information avaliable

Dispronil Chemical_Formula


Dispronil RX_link


Dispronil fda sheet

Dispronil FDA

Dispronil msds (material safety sheet)

Dispronil MSDS

Dispronil Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Dispronil Molecular Weight

337.449 g/mol

Dispronil Melting Point

163-164 oC

Dispronil H2O Solubility

1.1 mg/mL

Dispronil State


Dispronil LogP


Dispronil Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Dispronil Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Dispronil Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Dispronil Absorption

The bioavailability of oral doses is 40-45%.

Dispronil side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Dispronil Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Dispronil Organisms Affected

Humans and other mammals