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Cronol Brand names, Cronol Analogs

Cronol Brand Names Mixture

  • No information avaliable

Cronol Chemical_Formula


Cronol RX_link

Cronol fda sheet

Cronol FDA

Cronol msds (material safety sheet)

Cronol MSDS

Cronol Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Cronol Molecular Weight

337.449 g/mol

Cronol Melting Point

163-164 oC

Cronol H2O Solubility

1.1 mg/mL

Cronol State


Cronol LogP


Cronol Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Cronol Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Cronol Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Cronol Absorption

The bioavailability of oral doses is 40-45%.

Cronol side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Cronol Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Cronol Organisms Affected

Humans and other mammals