Famodine

Category

Famodine




Useful info

Famodine Brand names, Famodine Analogs

Famodine Brand Names Mixture

  • No information avaliable

    • Famodine Chemical_Formula

    C8H15N7O2S3

    Famodine RX_link

    http://www.rxlist.com/cgi/generic/famot.htm

    Famodine fda sheet

    Famodine FDA

    Famodine msds (material safety sheet)

    Famodine MSDS

    Famodine Synthesis Reference

    H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

    Famodine Molecular Weight

    337.449 g/mol

    Famodine Melting Point

    163-164 oC

    Famodine H2O Solubility

    1.1 mg/mL

    Famodine State

    Solid

    Famodine LogP

    -0.726

    Famodine Dosage Forms

    Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

    Famodine Indication

    For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

    Famodine Pharmacology

    Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

    Famodine Absorption

    The bioavailability of oral doses is 40-45%.

    Famodine Toxicity

    Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

    Famodine Patient Information

    Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
    hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
    reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
    physician if you are pregnant or nursing. Famotidine may be taken with or without food.
    Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
    suspension should be discarded after 30 days. Notify your physician if you develop black,
    tarry stools or coffee-ground vomit.

    Famodine Organisms Affected

    Humans and other mammals