Gastropen

Category

Gastropen




Useful info

Gastropen Brand names, Gastropen Analogs

Gastropen Brand Names Mixture

  • No information avaliable

    • Gastropen Chemical_Formula

    C8H15N7O2S3

    Gastropen RX_link

    http://www.rxlist.com/cgi/generic/famot.htm

    Gastropen fda sheet

    Gastropen FDA

    Gastropen msds (material safety sheet)

    Gastropen MSDS

    Gastropen Synthesis Reference

    H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

    Gastropen Molecular Weight

    337.449 g/mol

    Gastropen Melting Point

    163-164 oC

    Gastropen H2O Solubility

    1.1 mg/mL

    Gastropen State

    Solid

    Gastropen LogP

    -0.726

    Gastropen Dosage Forms

    Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

    Gastropen Indication

    For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

    Gastropen Pharmacology

    Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

    Gastropen Absorption

    The bioavailability of oral doses is 40-45%.

    Gastropen Toxicity

    Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

    Gastropen Patient Information

    Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
    hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
    reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
    physician if you are pregnant or nursing. Famotidine may be taken with or without food.
    Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
    suspension should be discarded after 30 days. Notify your physician if you develop black,
    tarry stools or coffee-ground vomit.

    Gastropen Organisms Affected

    Humans and other mammals