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Gastropen Brand names, Gastropen Analogs

Gastropen Brand Names Mixture

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Gastropen Chemical_Formula


Gastropen RX_link

Gastropen fda sheet

Gastropen FDA

Gastropen msds (material safety sheet)

Gastropen MSDS

Gastropen Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Gastropen Molecular Weight

337.449 g/mol

Gastropen Melting Point

163-164 oC

Gastropen H2O Solubility

1.1 mg/mL

Gastropen State


Gastropen LogP


Gastropen Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Gastropen Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Gastropen Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Gastropen Absorption

The bioavailability of oral doses is 40-45%.

Gastropen side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Gastropen Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Gastropen Organisms Affected

Humans and other mammals