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Famodil
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Famodil Brand names, Famodil Analogs

Famodil Brand Names Mixture

  • No information avaliable

Famodil Chemical_Formula

C8H15N7O2S3

Famodil RX_link

http://www.rxlist.com/cgi/generic/famot.htm

Famodil fda sheet

Famodil FDA

Famodil msds (material safety sheet)

Famodil MSDS

Famodil Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Famodil Molecular Weight

337.449 g/mol

Famodil Melting Point

163-164 oC

Famodil H2O Solubility

1.1 mg/mL

Famodil State

Solid

Famodil LogP

-0.726

Famodil Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Famodil Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Famodil Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Famodil Absorption

The bioavailability of oral doses is 40-45%.

Famodil side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Famodil Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Famodil Organisms Affected

Humans and other mammals