Famotidinum_[Latin]

Category

Famotidinum_[Latin]




Useful info

Famotidinum_[Latin] Brand names, Famotidinum_[Latin] Analogs

Famotidinum_[Latin] Brand Names Mixture

  • No information avaliable

    • Famotidinum_[Latin] Chemical_Formula

    C8H15N7O2S3

    Famotidinum_[Latin] RX_link

    http://www.rxlist.com/cgi/generic/famot.htm

    Famotidinum_[Latin] fda sheet

    Famotidinum_[Latin] FDA

    Famotidinum_[Latin] msds (material safety sheet)

    Famotidinum_[Latin] MSDS

    Famotidinum_[Latin] Synthesis Reference

    H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

    Famotidinum_[Latin] Molecular Weight

    337.449 g/mol

    Famotidinum_[Latin] Melting Point

    163-164 oC

    Famotidinum_[Latin] H2O Solubility

    1.1 mg/mL

    Famotidinum_[Latin] State

    Solid

    Famotidinum_[Latin] LogP

    -0.726

    Famotidinum_[Latin] Dosage Forms

    Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

    Famotidinum_[Latin] Indication

    For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

    Famotidinum_[Latin] Pharmacology

    Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

    Famotidinum_[Latin] Absorption

    The bioavailability of oral doses is 40-45%.

    Famotidinum_[Latin] Toxicity

    Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

    Famotidinum_[Latin] Patient Information

    Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
    hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
    reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
    physician if you are pregnant or nursing. Famotidine may be taken with or without food.
    Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
    suspension should be discarded after 30 days. Notify your physician if you develop black,
    tarry stools or coffee-ground vomit.

    Famotidinum_[Latin] Organisms Affected

    Humans and other mammals