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Hacip Brand names, Hacip Analogs

Hacip Brand Names Mixture

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Hacip Chemical_Formula


Hacip RX_link


Hacip fda sheet

Hacip FDA

Hacip msds (material safety sheet)

Hacip MSDS

Hacip Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Hacip Molecular Weight

337.449 g/mol

Hacip Melting Point

163-164 oC

Hacip H2O Solubility

1.1 mg/mL

Hacip State


Hacip LogP


Hacip Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Hacip Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Hacip Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Hacip Absorption

The bioavailability of oral doses is 40-45%.

Hacip side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Hacip Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Hacip Organisms Affected

Humans and other mammals