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Famodar
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Famodar Brand names, Famodar Analogs

Famodar Brand Names Mixture

  • No information avaliable

Famodar Chemical_Formula

C8H15N7O2S3

Famodar RX_link

http://www.rxlist.com/cgi/generic/famot.htm

Famodar fda sheet

Famodar FDA

Famodar msds (material safety sheet)

Famodar MSDS

Famodar Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Famodar Molecular Weight

337.449 g/mol

Famodar Melting Point

163-164 oC

Famodar H2O Solubility

1.1 mg/mL

Famodar State

Solid

Famodar LogP

-0.726

Famodar Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Famodar Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Famodar Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Famodar Absorption

The bioavailability of oral doses is 40-45%.

Famodar side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Famodar Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Famodar Organisms Affected

Humans and other mammals