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Famotin
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Famotin Brand names, Famotin Analogs

Famotin Brand Names Mixture

  • No information avaliable

Famotin Chemical_Formula

C8H15N7O2S3

Famotin RX_link

http://www.rxlist.com/cgi/generic/famot.htm

Famotin fda sheet

Famotin FDA

Famotin msds (material safety sheet)

Famotin MSDS

Famotin Synthesis Reference

H. Yasufumi et al.; U.S. Pat. 4,283,408 (1981)

Famotin Molecular Weight

337.449 g/mol

Famotin Melting Point

163-164 oC

Famotin H2O Solubility

1.1 mg/mL

Famotin State

Solid

Famotin LogP

-0.726

Famotin Dosage Forms

Oral tablets; Rapid disintergrating tablets; Suspension; Injectable solution

Famotin Indication

For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).

Famotin Pharmacology

Famotidine, a competitive histamine H2-receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Famotin Absorption

The bioavailability of oral doses is 40-45%.

Famotin side effects and Toxicity

Intravenous, mouse: LD50 = 244.4mg/kg; Oral, mouse: LD50 = 4686 mg/kg. Symptoms of overdose include emesis, restlessness, pallor of mucous membranes or redness of mouth and ears, hypotension, tachycardia and collapse.

Famotin Patient Information

Famotidine is used to treat stomach and duodenal (upper small intestine) ulcers;
hypersecretory (increased acid secretion) conditions; heartburn and gastroesophageal
reflux disease (stomach contents bubbling into the esophagus causing pain). Notify your
physician if you are pregnant or nursing. Famotidine may be taken with or without food.
Shake the oral suspension vigorously for 5-10 seconds before taking. Unused oral
suspension should be discarded after 30 days. Notify your physician if you develop black,
tarry stools or coffee-ground vomit.

Famotin Organisms Affected

Humans and other mammals