trans-Tranexamic acid

Antiemetics

trans-Tranexamic acid Brand names, trans-Tranexamic acid Analogs

trans-Tranexamic acid Brand Names Mixture

No information avaliable

trans-Tranexamic acid Chemical_Formula

C₂₁H₂₈N₂O₅

trans-Tranexamic acid RX_link

http://www.rxlist.com/cgi/generic3/trimethbenz.htm

trans-Tranexamic acid fda sheet

trans-Tranexamic_acid FDA

trans-Tranexamic acid msds (material safety sheet)

trans-Tranexamic_acid MSDS

trans-Tranexamic acid Synthesis Reference

No information avaliable

trans-Tranexamic acid Molecular Weight

388.458 g/mol

trans-Tranexamic acid Melting Point

188.7 ^oC

trans-Tranexamic acid H₂O Solubility

40 mg/L

trans-Tranexamic acid State

Solid

trans-Tranexamic acid LogP

2.784

trans-Tranexamic acid Dosage Forms

Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)

trans-Tranexamic acid Indication

For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.

trans-Tranexamic acid Pharmacology

Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.

trans-Tranexamic acid Absorption

The relative bioavailability of the capsule formulation compared to the solution is 100%.

trans-Tranexamic acid side effects and Toxicity

Oral LD₅₀ in mice is 1600 mg/kg.

trans-Tranexamic acid Patient Information