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trans-Amcha Brand names, trans-Amcha Analogs

trans-Amcha Brand Names Mixture

  • No information avaliable

trans-Amcha Chemical_Formula

C21H28N2O5

trans-Amcha RX_link

http://www.rxlist.com/cgi/generic3/trimethbenz.htm

trans-Amcha fda sheet

trans-Amcha FDA

trans-Amcha msds (material safety sheet)

trans-Amcha MSDS

trans-Amcha Synthesis Reference

No information avaliable

trans-Amcha Molecular Weight

388.458 g/mol

trans-Amcha Melting Point

188.7 oC

trans-Amcha H2O Solubility

40 mg/L

trans-Amcha State

Solid

trans-Amcha LogP

2.784

trans-Amcha Dosage Forms

Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)

trans-Amcha Indication

For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.

trans-Amcha Pharmacology

Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.

trans-Amcha Absorption

The relative bioavailability of the capsule formulation compared to the solution is 100%.

trans-Amcha side effects and Toxicity

Oral LD50 in mice is 1600 mg/kg.

trans-Amcha Patient Information

No information avaliable

trans-Amcha Organisms Affected

Humans and other mammals