Emorhalt

Antiemetics

Emorhalt Brand names, Emorhalt Analogs

Emorhalt Brand Names Mixture

No information avaliable

Emorhalt Chemical_Formula

C₂₁H₂₈N₂O₅

Emorhalt RX_link

http://www.rxlist.com/cgi/generic3/trimethbenz.htm

Emorhalt fda sheet

Emorhalt FDA

Emorhalt msds (material safety sheet)

Emorhalt MSDS

Emorhalt Synthesis Reference

No information avaliable

Emorhalt Molecular Weight

388.458 g/mol

Emorhalt Melting Point

188.7 ^oC

Emorhalt H₂O Solubility

40 mg/L

Emorhalt State

Solid

Emorhalt LogP

2.784

Emorhalt Dosage Forms

Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)

Emorhalt Indication

For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.

Emorhalt Pharmacology

Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.

Emorhalt Absorption

The relative bioavailability of the capsule formulation compared to the solution is 100%.

Emorhalt side effects and Toxicity

Oral LD₅₀ in mice is 1600 mg/kg.

Emorhalt Patient Information