tranexmic acid
tranexmic acid Brand names, tranexmic acid Analogs
tranexmic acid Brand Names Mixture
- No information avaliable
tranexmic acid Chemical_Formula
C21H28N2O5
tranexmic acid RX_link
http://www.rxlist.com/cgi/generic3/trimethbenz.htm
tranexmic acid fda sheet
tranexmic acid msds (material safety sheet)
tranexmic acid Synthesis Reference
No information avaliable
tranexmic acid Molecular Weight
388.458 g/mol
tranexmic acid Melting Point
188.7 oC
tranexmic acid H2O Solubility
40 mg/L
tranexmic acid State
Solid
tranexmic acid LogP
2.784
tranexmic acid Dosage Forms
Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)
tranexmic acid Indication
For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
tranexmic acid Pharmacology
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
tranexmic acid Absorption
The relative bioavailability of the capsule formulation compared to the solution is 100%.
tranexmic acid side effects and Toxicity
Oral LD50 in mice is 1600 mg/kg.
tranexmic acid Patient Information
No information avaliable
tranexmic acid Organisms Affected
Humans and other mammals
