Tamcha

Antiemetics

Tamcha Brand names, Tamcha Analogs

Tamcha Brand Names Mixture

No information avaliable

Tamcha Chemical_Formula

C₂₁H₂₈N₂O₅

Tamcha RX_link

http://www.rxlist.com/cgi/generic3/trimethbenz.htm

Tamcha fda sheet

Tamcha FDA

Tamcha msds (material safety sheet)

Tamcha MSDS

Tamcha Synthesis Reference

No information avaliable

Tamcha Molecular Weight

388.458 g/mol

Tamcha Melting Point

188.7 ^oC

Tamcha H₂O Solubility

40 mg/L

Tamcha State

Solid

Tamcha LogP

2.784

Tamcha Dosage Forms

Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)

Tamcha Indication

For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.

Tamcha Pharmacology

Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.

Tamcha Absorption

The relative bioavailability of the capsule formulation compared to the solution is 100%.

Tamcha side effects and Toxicity

Oral LD₅₀ in mice is 1600 mg/kg.

Tamcha Patient Information