Cyklokapron
Cyklokapron Brand names, Cyklokapron Analogs
Cyklokapron Brand Names Mixture
- No information avaliable
Cyklokapron Chemical_Formula
C21H28N2O5
Cyklokapron RX_link
http://www.rxlist.com/cgi/generic3/trimethbenz.htm
Cyklokapron fda sheet
Cyklokapron msds (material safety sheet)
Cyklokapron Synthesis Reference
No information avaliable
Cyklokapron Molecular Weight
388.458 g/mol
Cyklokapron Melting Point
188.7 oC
Cyklokapron H2O Solubility
40 mg/L
Cyklokapron State
Solid
Cyklokapron LogP
2.784
Cyklokapron Dosage Forms
Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)
Cyklokapron Indication
For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
Cyklokapron Pharmacology
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Cyklokapron Absorption
The relative bioavailability of the capsule formulation compared to the solution is 100%.
Cyklokapron side effects and Toxicity
Oral LD50 in mice is 1600 mg/kg.
Cyklokapron Patient Information
No information avaliable
Cyklokapron Organisms Affected
Humans and other mammals
