Tranhexamic acid
Tranhexamic acid Brand names, Tranhexamic acid Analogs
Tranhexamic acid Brand Names Mixture
- No information avaliable
Tranhexamic acid Chemical_Formula
C21H28N2O5
Tranhexamic acid RX_link
http://www.rxlist.com/cgi/generic3/trimethbenz.htm
Tranhexamic acid fda sheet
Tranhexamic acid msds (material safety sheet)
Tranhexamic acid Synthesis Reference
No information avaliable
Tranhexamic acid Molecular Weight
388.458 g/mol
Tranhexamic acid Melting Point
188.7 oC
Tranhexamic acid H2O Solubility
40 mg/L
Tranhexamic acid State
Solid
Tranhexamic acid LogP
2.784
Tranhexamic acid Dosage Forms
Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)
Tranhexamic acid Indication
For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
Tranhexamic acid Pharmacology
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Tranhexamic acid Absorption
The relative bioavailability of the capsule formulation compared to the solution is 100%.
Tranhexamic acid side effects and Toxicity
Oral LD50 in mice is 1600 mg/kg.
Tranhexamic acid Patient Information
No information avaliable
Tranhexamic acid Organisms Affected
Humans and other mammals
