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Nitrogen mustard Brand names, Nitrogen mustard Analogs

Nitrogen mustard Brand Names Mixture

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Nitrogen mustard Chemical_Formula


Nitrogen mustard RX_link

Nitrogen mustard fda sheet

Nitrogen_mustard FDA

Nitrogen mustard msds (material safety sheet)

Nitrogen_mustard MSDS

Nitrogen mustard Synthesis Reference

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Nitrogen mustard Molecular Weight

304.212 g/mol

Nitrogen mustard Melting Point

65 oC

Nitrogen mustard H2O Solubility

1.24E+004 mg/L

Nitrogen mustard State


Nitrogen mustard LogP


Nitrogen mustard Dosage Forms


Nitrogen mustard Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Nitrogen mustard Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Nitrogen mustard Absorption

No information avaliable

Nitrogen mustard side effects and Toxicity

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Nitrogen mustard Patient Information

No information avaliable

Nitrogen mustard Organisms Affected

Humans and other mammals