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Linfolizin Brand names, Linfolizin Analogs

Linfolizin Brand Names Mixture

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Linfolizin Chemical_Formula


Linfolizin RX_link

Linfolizin fda sheet

Linfolizin FDA

Linfolizin msds (material safety sheet)

Linfolizin MSDS

Linfolizin Synthesis Reference

No information avaliable

Linfolizin Molecular Weight

304.212 g/mol

Linfolizin Melting Point

65 oC

Linfolizin H2O Solubility

1.24E+004 mg/L

Linfolizin State


Linfolizin LogP


Linfolizin Dosage Forms


Linfolizin Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Linfolizin Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Linfolizin Absorption

No information avaliable

Linfolizin side effects and Toxicity

No information avaliable

Linfolizin Patient Information

No information avaliable

Linfolizin Organisms Affected

Humans and other mammals