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Leukoran Brand names, Leukoran Analogs

Leukoran Brand Names Mixture

  • No information avaliable

Leukoran Chemical_Formula


Leukoran RX_link


Leukoran fda sheet

Leukoran FDA

Leukoran msds (material safety sheet)

Leukoran MSDS

Leukoran Synthesis Reference

No information avaliable

Leukoran Molecular Weight

304.212 g/mol

Leukoran Melting Point

65 oC

Leukoran H2O Solubility

1.24E+004 mg/L

Leukoran State


Leukoran LogP


Leukoran Dosage Forms


Leukoran Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Leukoran Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Leukoran Absorption

No information avaliable

Leukoran side effects and Toxicity

No information avaliable

Leukoran Patient Information

No information avaliable

Leukoran Organisms Affected

Humans and other mammals