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Chlocambucil Brand names, Chlocambucil Analogs

Chlocambucil Brand Names Mixture

  • No information avaliable

Chlocambucil Chemical_Formula


Chlocambucil RX_link

Chlocambucil fda sheet

Chlocambucil FDA

Chlocambucil msds (material safety sheet)

Chlocambucil MSDS

Chlocambucil Synthesis Reference

No information avaliable

Chlocambucil Molecular Weight

304.212 g/mol

Chlocambucil Melting Point

65 oC

Chlocambucil H2O Solubility

1.24E+004 mg/L

Chlocambucil State


Chlocambucil LogP


Chlocambucil Dosage Forms


Chlocambucil Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Chlocambucil Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Chlocambucil Absorption

No information avaliable

Chlocambucil side effects and Toxicity

No information avaliable

Chlocambucil Patient Information

No information avaliable

Chlocambucil Organisms Affected

Humans and other mammals