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Chloraminophen Brand names, Chloraminophen Analogs

Chloraminophen Brand Names Mixture

  • No information avaliable

Chloraminophen Chemical_Formula

C14H19Cl2NO2

Chloraminophen RX_link

http://www.rxlist.com/cgi/generic2/leukeran.htm

Chloraminophen fda sheet

Chloraminophen FDA

Chloraminophen msds (material safety sheet)

Chloraminophen MSDS

Chloraminophen Synthesis Reference

No information avaliable

Chloraminophen Molecular Weight

304.212 g/mol

Chloraminophen Melting Point

65 oC

Chloraminophen H2O Solubility

1.24E+004 mg/L

Chloraminophen State

Solid

Chloraminophen LogP

3.25

Chloraminophen Dosage Forms

Tablet

Chloraminophen Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Chloraminophen Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Chloraminophen Absorption

No information avaliable

Chloraminophen side effects and Toxicity

No information avaliable

Chloraminophen Patient Information

No information avaliable

Chloraminophen Organisms Affected

Humans and other mammals